7/26/2023 0 Comments Kate netflix review![]() I think the 3rd act moved far to quickly and became a different genre almost when it got to that point that was a little weird but also had really good action then. The action was well done, not a ton of moves and choreography we haven't seen before, but there was a couple moves I was like dang. I think Kate and Anis performances were pretty good but whoever woody Harrelsons character name was I can't remember was a little more eh. The plot I think became quite confusing once Ani was introduced which led me in the end after it was over to have to look up what the ending meant cause I didn't understand. I think it was a good popcorn movie and a tiny bit more. Within the comment sections, recommendations for non-Netflix content will sometimes be allowed. The primary focus of this sub should be content available on Netflix, and all top level recommendations and questions should be about Netflix. ![]() Hover over to read.Īdd regional flair tags to your submissions so we know what Netflix region you're posting from CLICK HERE FOR MORE INFORMATION Please write a short blurb either in the submission title or the text if you do a self post to explain why this movie/show is worth watching.Īdd spoiler tags as a courtesy. Please link to the description page of the movie or show you are posting. ![]() If the same title appears simultaneously in the top 50, it may be removed at the mod's discretion. Stop complaining about reposts and stop messaging the mods about it. ![]() The mods are leaving it up to the community to utilize downvotes if they feel that reposts are too excessive. The front page of this subreddit is meant to be a living representation of quality content on Netflix and you might see the same submissions multiple times. Reposts are not only allowed, but are encouraged to some extent. The primary purpose of /r/NetflixBestOf is to shitpost about Breaking Bad. ![]()
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7/26/2023 0 Comments Bitcoin core developer![]() ![]() The bitcoin blockchain is a public ledger that records bitcoin transactions. According to the University of Cambridge, bitcoin has emitted an estimated 200 million tonnes of carbon dioxide since its launch, or about 0.04% of all carbon dioxide released since 2009. Its proof-of-work algorithm for bitcoin mining is designed to be computationally difficult, which requires the consumption of increasing quantities of electricity, the generation of which has contributed to climate change. The environmental effects of bitcoin are substantial. ![]() Iran has used bitcoin to bypass sanctions.īitcoin has been described as an economic bubble by at least eight recipients of the Nobel Memorial Prize in Economic Sciences. Ukraine has accepted cryptocurrency donations to fund the resistance to the 2022 Russian invasion. El Salvador has adopted Bitcoin as legal tender, although use by merchants remains low. A few governments have used bitcoin in some capacity. The Library of Congress reports that, as of November 2021, nine countries have fully banned bitcoin use, and a further forty-two have implicitly banned it. It is a compound of the words bit and coin. The word "bitcoin" was defined in a white paper published on October 31, 2008. ![]() The currency began use in 2009, when its implementation was released as open-source software. The cryptocurrency was invented in 2008 by an unknown person or group of people using the name Satoshi Nakamoto. īitcoin transactions are verified by network nodes through cryptography and recorded in a public distributed ledger called a blockchain. Because the token has characteristics of money, it can be thought of as a digital currency. The user can update the ledger, assigning some of their bitcoin to another entry in the ledger. The protocol specifies that the entry indicates an amount of a token, bitcoin with a minuscule b. In order to add to the ledger, a user must prove they control an entry in the ledger. Without proper rendering support, you may see question marks, boxes, or other symbols.īitcoin ( abbreviation: BTC or XBT sign: ₿) is a protocol which implements a highly available, public, permanent, and decentralized ledger. This article contains special characters. Initially ₿50 per block, halved every 210,000 blocks ![]() 7/26/2023 0 Comments Maneater caviar key landmarks![]() You can either follow the storyline or if you’ve got the skills, jump some of the sea walls and explore at your own pace. Getting to new areas, or unlocking new areas, in Maneater is easy. You can refer to our Maneater collectibles guide for maps containing all collectibles and grotto locations to make this a bit easier. ![]() If you do find yourself exploring the ocean ahead of the story’s progression, make sure you know how to find grottos, as you will want to use it as quick travel point in the future. This is likely a good thing, as the area may be too difficult for those new to Dead Horse Lake. For example, to the southeast of Dead Horse Lake is a large gate preventing you access to Caviar Key. However, jumping seawalls isn’t always an option. Sometimes giant seawalls block access to other areas. From here, it’s only a short swim into the Sapphire Bay. But for those that want to skip ahead of the story and do some more freeform exploring, you can do that too.īy the time you reach Dead Horse Lake, you should be capable of jumping the sea wall to the west and getting into Golden Shores. Finish an area and you will be directed to the next one. This system is in place throughout the entire campaign. For example, after clearing out all the objectives in Fawtick Bayou, the game will highlight the Dead Horse Lake, a clear indication that you should head there next. Sometimes these are blocked by age-locked gates.įirst thing’s first, as you progress through the storyline, you will automatically be directed to the area you should be focused on next. The story will always point you to the area you should visit next. It can be a bit tricky to find which area you should go to next and whether or not you’ve got the skills to get there. At the start of the game, you find yourself in a brackish bayou, but soon enough you’ll want to start pushing into new territory. Maneater includes eight unique areas for players to explore. ![]() As one of the most powerful sharks in the sea, you’ve got a few options for unlocking new regions. But one struggle some players might face is getting to a new area in Maneater. Each of the individual areas offers a unique biodiversity that sets them apart from each other. ![]() 7/26/2023 0 Comments Menucal drug![]() At about midday on the 14th August, 1976, a customs officer on duty in the green channel at Terminal 3 at Heathrow Airport intercepted Miss Henao on her arrival from Bogota and her suitcase was found to have a false compartment. We are thrilled to be a part of this development program and believe it holds significant potential as an effective treatment for ovarian cancer patients.The facts of the offences may be summarised as follows. ![]() Sung Chul Kim, President and Founder of Algok Bio, said, "As the only small molecule drug with a unique mechanism of action currently targeting FRα, the efficacy and safety profiles in early clinical studies were highly promising and competitive with other antibody-drug conjugate drugs. I wish Algok Bio the very best to develop this drug for patients with ovarian cancer and other FRα-overexpressing cancers."ĭr. "This drug has significant potential as a possible future treatment for ovarian cancer and I am thrilled that it is now advancing to the next stage of clinical development. In a similar stage of development, idetrexed has shown comparable efficacy to drugs such as antibody drug conjugates that have gone on to successful late phase development. Professor Udai Banerji, principal investigator of the idetrexed phase I study and co-director of Drug Development at the ICR and The Royal Marsden, said, "Idetrexed is a small molecule targeting FRα-overexpressing cancers that has shown significant single agent activity in phase I clinical trials. The development of idetrexed by Algok Bio holds significant promise for the treatment of these cancers, and the exclusive license agreement with BTG represents a major milestone in the development of this innovative therapy. ![]() Kidney, lung, colorectal, and gastric cancers also exhibit varying degrees of expression. More than 90% of ovarian cancer cases express FRα, with high levels of overexpression also observed in endometrial, triple-negative breast cancer, and mesothelioma. Idetrexed is a potent thymidylate synthase inhibitor that triggers cell death while selectively targeting the alpha folate receptor (FRα), which is highly expressed in cancer cells compared to normal tissues across a variety of solid tumors.Ī phase I study conducted by the ICR and The Royal Marsden, the results of which were published in Clinical Cancer Research last year, treated 109 cancer patients, including ovarian cancer patients resistant to platinum-based chemotherapy, with idetrexed.Īmong 25 platinum-resistant ovarian cancer patients with high or medium expression of FRα who received the recommended phase II dose, tumor shrinkage was observed in nine patients (overall response rate 36% 95% CI, 18–57.5).Īccording to the World Health Organization, ovarian cancer is the seventh most commonly diagnosed cancer in women worldwide, with over 300,000 new cases diagnosed each year. ![]() Additional clinical programs exploring other indications and combination regimens with standard care will also be pursued. Under the agreement, Algok Bio will make an upfront payment to BTG and additional payments contingent on achieving specific regulatory and sales milestones, as well as tiered royalty payments.Īlgok Bio will soon initiate pivotal studies for registering idetrexed for ovarian cancer treatment. Cancer Research UK also helped to fund earlier research.Īlgok Bio's exclusive license agreement with BTG grants the former the rights to develop and commercialize idetrexed worldwide. Idetrexed is set to undergo the larger trial thanks to a new agreement between US-based pharmaceutical company Algok Bio and BTG International, which partnered with the ICR earlier in the drug's development. The phase II trial will further test idetrexed's effectiveness and safety in a larger group of patients, specifically with ovarian cancer. ![]() It has already shown particular promise in ovarian cancer in a first-in-human, phase I trial led by researchers at the ICR and our partner hospital, The Royal Marsden NHS Foundation Trust. The drug, called idetrexed and formerly known by experimental drug names including BTG945, ONX-0901 and CT900, was created by scientific teams in what is now the ICR's Center for Cancer Drug Discovery. ![]() ![]() ![]() All versions are powered by a 2.5L 4-cylinder engine making 170 horsepower and 175 pound-feet of torque, which Nissan claims is tops in its class. Nissan keeps things pretty simple with powertrain options for the Rogue. With available three-row seating, the Rogue is possibly one of the most versatile vehicles available at such a low price. The Rogue starts at just over $23,000, while even the top trim model with all-wheel drive can be had for under $30,000. In order to remain competitive, Nissan has equipped the Rogue with a bevy of features and some very reasonable base prices. This puts the Rogue in direct competition with vehicles such as the Toyota RAV4 and the Honda CR-V, two vehicles with several generations and years of success under their belts. ![]() The Nissan Rogue is a small SUV/crossover, offering a more car-like driving experience than the more hard-core Nissan Xterra. Model ChangesĪffordable high-tech features optional third row seating available all-wheel drive Model Value In addition, a Siri Eyes Free now comes with both SL trimmed Rogues as well as the Rogue SV when equipped with the Premium Package. A forward emergency braking system has been added to help prevent accidents, while NissanConnect Services are also now standard on the SL. Again, my vehicle did not alert me that he was anywhere near my car meanwhile he was extremely close.The Rogue SL trim gets several notable enhancements for 2016. I immediately stopped my vehicle giving him the right way and thanking god that I did not hit him. The third incident happened on Wednesday, Novemat approximately 2:46pm, I had been driving cautiously as I do adhering to the speed limit, I noticed a bicyclist pedaling along his way, it seems as if we were heading towards the same direction so I proceeded to drive cautiously as I was approaching an intersection to make a left, I checked all three mirrors and even looked back didn't see him so I began to make a left as I was turning left I could see him in my peripheral vision approaching the cross walk. I couldn't live with myself if I caused bodily injury to my son that could potentially cause grave danger, loss of a limb or death. Again, the vehicle failed to alert me that someone was in an area that I couldn't see. Mom! stop!!! I said, what happened, he said you almost ran me over. The second, incident happened when I returned home with the groceries and my children were exiting the vehicle with the groceries, my son then came back to check to see if I needed something else carried upstairs and I did not see my son as I began pulling off, my son children both yelled in voices of distress. The first 2 happened shortly after I left the supermarket, I was pulling out of a parking spot & checked all my mirrors and windows prior to pulling out when I felt in gut that something wasn't right, I covered my brakes while slowly pulling out and asked my son to check out on the right side of the vehicle and there had been a child inches away from my car and I did not see nor was alerted by the vehicle. Three separate incidents have happened since leasing this car on Sunday evening on November 1, 2020. Having been placed in rental vehicle that has the bsw warning embedded in the sideview mirror itself I find that to be a much more immediate attention grabber than Nissan's bsw construct in my vehicle such that I have purchased aftermarket bsw mirrors to place on my sideview mirrors to prevent /assist with this issue. I looked, looked again and did not see the vehicle in my blind spot and I genuinely feel that the bsw in this vehicle is not sufficient to alert a driver in those conditions in a manner that garners the drivers immediate attention. I was in blind spot collision accident on in va on 395s at 3:30pm est. The audible portion is not adjustable in volume and when on a busy interstate with navigation guiding you it is very difficult to hear. The bsw is positioned inside the vehicle to the left and right near the sideview mirrors but obscured enough in one's vision that it does not gain ready attention. ![]() The bsw worked however the engineering of this particular bsw on this model is such that I feel it did not provide the queues in such a manner as to gain immediate visual/audible attention. ![]() 7/26/2023 0 Comments Screenie for imvu![]() ![]() ![]() PM me all screenies my avatarname GlamRebel. And all the screenshots will be posted on my blog for all who submitted. 25 Pose Screenie Room v2 ' / ( ( ( ) Descubre como vestirte, conversar y divertirte en IMVU. Okay soo now I want you my readers to send me some screenshots of their avatars base on my tips. Throw on some heels and a handbag and you will get a phenamonal outfit. It is lit with soft shadowed lighting similar to that of the Shop room in the client. Diiva has some pretty Maxi Skirt that are high and low in pretty colors. Large open green screenshot room with no walls, floor, or ceiling. Maxi Dresses where? Low, Bihitchy and my favorite developer Pierce has a couple of pastel color dress check them out. For more on the IMVU Creator program, which lets you create items for sale in the IMVU catalog, please click here. Great developer such as Martha and my Twinnie WannaMonroe has a few high and low dresses that are amazing. Maxi Skirt & Dresses (high & low included) you say? Omg your a PRO. The lighting is clear and shadow free to best show off your products. Its very wearable with almost every color just dont over do it. Large open green screenshot room with no walls, floor, or ceiling. American Flag print stuff? Your getting the hang of it! AFP is very vintage (I know I know me and that vintage word but I love itt :D). Baggy oversized jean Jackets w gradient hair? HELLLO VINTAGE’S CALLING, May want to answer that!Ħ. Handbangs w baggy pants? You betcha! Yes skinny are fashionable but sometimes you just wanna get lose and baggy! I say go for it!ĥ. Hey take a chance and try colors such as, hot / rose / nude pink, light / navy blue, sunbright yellow, leaf/ bright green, purple, turquoise and black.Ĥ. Even black lip color is very fashionable and vintage :). Select any image on your screen and find dozens similar images. Solid bright colors for lip gloss? HELL YEAHH! Go for it. Similar image search Find similar images. With the new imvu desktop, you cloth, furniture, accessories and. If you throw an outfit together and you simply adore it freak what people say. 3.3K views 1 year ago This is comparison between the latest imvu desktop version display and the old original imvu client. Where games like Roblox, a multiplayer game where you can socialize, have a common control scheme by keyboard, IMVU is limited to movement with a. If you need to find someone, you can use the name checker. Your added contacts can join your private locations to avoid interruption from other players. ![]() Fashion and music is the only thing that allows us to be ourselves. These involve private and public locations. Be creative dont be afraid to show your true color :).Ģ. For example if you have onacheetah print pants, dont try to put on cheetah top. It keeps growing because it's a look at things to come. Social media users have more or less hidden behind avatars and screen names since the bulletin board days IMVU simply takes it to new levels. IMVU Cache Cleaner 5.0.1, Fixed compatibility issues with Windows XP. A Google image search will let you peep through IMVU's portal, if you're curious. Havent forgotten about Screenie, but unfortunately most of the source got wiped. There's a lot to do and to learn, including a whole subculture. But, like a lot of things, you have to experience IMVU to understand it. We had no problems whatsoever with IMVU's interface or with the people we met. We're not going to bore you or amuse you with our personal exploits, except to say we're all noobs once. There's also a security question to make sure you're not a machine. To create a screen name and password, you'll have to provide some info, such as date of birth and a valid email address. The avatars are all young, attractive, and a bit edgy, but in different (and good) ways. There are nine each of male and female avatars to choose from, and you can choose from either set on IMVU, you can't judge anyone or take anything for granted, and you have to interact with people to learn about them. Signing up for IMVU is easy and starts with choosing a free avatar. It's a fun way to learn stuff like how to run a small business or market a product, too. You can design, make, buy, and sell things like clothes and accessories, earn credit in IMVU's virtual economy, and get noticed. But IMVU is much more than a 3D chat room: it's a real simulated world (or the real world, simulated). As with other virtual communities, you can make friends among IMVU's millions of users. IMVU is "the world's largest 3D Chat and Dress-Up community." Launched in 2004, Instant Messaging Virtual Universe is simple in concept: Combine the social networking power of IM chat with a 3D virtual "universe." Participants create elaborate new identities, called avatars, that give free rein to self-expression. ![]() 7/26/2023 0 Comments Mixchecker from audified![]()
7/26/2023 0 Comments Club noto philly![]() Snag your tickets today before this exclusive Philly event sells out. Roc Nation is a full-service entertainment company, inclusive of artist and athlete management, label, publishing, touring, film / TV and new ventures. Ring in this NYE with a history-making show and an unstoppable party.Ĭome ring in the New Year with a nightclub that’s all about getting loose and letting go. NOTO is an immense, bi-level nightlife citadel. As one of Philly’s premier mega-clubs, NOTO boasts cutting-edge technology, including HD screens and LED walls, all wrapped in luxurious design. Disco balls, mirrored subway tile, leather booths, and a massive chandelier are just some of the accents that take this party haven over the top. Its next-level sound system is perfectly outfitted for its acclaimed program of top DJs including Travis Scott, Cheat Codes, Zedd, MAKJ, and many more. If you want to upgrade your night, even more, you’ll love the VIP packages that provide you with deluxe perks like reserved seating and bottle service. Programming varies depending on the night, for more information check our upcoming events. Then raise your complimentary glass of chilled champagne high into the air and bid the year adieu with a roaring midnight countdown. NOTO is an immense, bi-level nightlife citadel. Penn Palace Night Club, Heat Bar & Night Club, NOTO Philadelphia. ![]() Hollywood will be spinning the best Top 40, dance, and hip-hop beats all night long. Zillow has 6331 homes for sale in Philadelphia PA. NOTO, short for 'Not of the Ordinary,' is hosting three preview nights for Philadelphians to check out the new nightclub. Come out and play at an explosive year-end bash full of bright lights, awesome music, and all-out revelry.Ĭome indulge in the 5 hour premium open bar and quench your thirst with NOTO's delicious cocktails before you bust a move on the dance floor, where DJ Mr. I chatted with the doormen, who were very nice, most came from top clubs in Philly, a few moved to Philly from NYC to work at the club, they suggested I come back in an hour. Man shot after Philly nightclub fight, walks to closed Hahnemann for help. Philly’s best nightclub is members-only, but they’re dropping the velvet ropes to offer you a party haven full of New Year’s Eve magic. NOTO is on the right) I’m so punctual, I saw that the party started at 9PM so that’s when I got there. ![]() NOTO is just for grown-ups this New Year's Eve at NOTO in Philadelphia. ![]() 7/26/2023 0 Comments Burly men at sea guide![]() ![]() Ensure that no evidence goes undiscovered by adjusting the viewpoint to get a good look at every scene, and zoom right in on any suspicious areas. ![]() Use the device to analyse witnesses moods as they testify - unearth the hidden feelings behind their words and challenge their testimonies to unravel the truth!Ĭrime scenes are now simpler to snoop around, and evidence easier to analyse than before. Her Mood Matrix can highlight the emotions of a witness, giving a whole new perspective on witness statements. Joining Phoenix are young Attorney Apollo Justice and newcomer Associate Attorney Athena Cykes, who brings her own tricks to the courtroom. Presented in full 3D for the first time ever, the series trademark over-the-top character reactions come bursting to life in exciting new ways, while retaining the feel of the previous titles 2D artwork. The quirky gameplay of previous Ace Attorney titles is back in force: investigate crime scenes to uncover clues with the Nintendo 3DS Touch Screen and go head-to-head with lawyers and law-breakers in the courts. When an explosion rocks the courts, its up to the Wright Anything Agency to bring the hammer of justice down on those responsible in an adventure filled with all the swerves, shenanigans and stepladders that the Ace Attorney series is known for. Over 2 hours of exclusive developer commentaryĮight years since he last stepped into the courtroom, Phoenix Wright makes his triumphant return in Phoenix Wright: Ace Attorney - Dual Destinies, exclusively available in Nintendo eShop on Nintendo 3DS. Classic score re-recorded with a full live orchestra Grim Fandango still stands as a classic of the genre, with unforgettable characters and unique combination of film noir and Mexican folklore. Grim Fandango's epic story of four years in the life (or death) of Manny Calavera, travel agent to the dead, has been remastered to look, sound, and control even better than when it won GameSpot's Game of the Year award upon its original launch. One of the most acclaimed adventure games of all time is now back, better than ever. Help Manny untangle himself from a conspiracy that threatens his very salvation. He sells luxury packages to souls on their four-year journey to eternal rest. Meet Manny Calavera, travel agent at the Department of Death. Something's rotten in the land of the dead, and you're being played for a sucker. ![]() 7/25/2023 0 Comments Function notion definition math![]() Let the domain be the set of students at Hogwarts, and the range is the set of houses (Gryffindor, Hufflepuff, Ravenclaw and Slytherin). An example would be the houses at Hogwarts. However, a function can still be well defined when there are multiple inputs for the same output. In all of the functions in this last applet, there is only one input for each output – only one solution. Multiple inputs for the same output is OK In this case, we set up an equation and solve it: Sometimes we may have the output of a function and we are required to calculate the input: It is not well defined as there is a number that does not have an answer – that is. We would say that this is not a well defined function. The functions in the following applet are defined for all values of :Ī function is well defined when for every input, there is one output. If a domain is not stated, it is assumed that the domain includes all real numbers. So there is no value for for this function. (b) Zero is usually an easy calculation! The ordered pair is a member of this relation. (a) The ordered pair is a member of this relation. We can define a function by stating an expression and a domain. one or more variables (in our example, ).Some ordered pairs generated by this function are: The first element in the ordered pair is the variable, the second element is the value of the expression. We can express the same relation using function notation:Ī function, like a relation, is a set of ordered pairs. If it crosses more than once, the graph does not represent a function. Interpretation 2: When looking at a graph, if you put ruler vertically on any value, and if it only every crosses a graph once, the graph represents a function. ![]() Answer: or – this relation is not a function. Interpretation 1: When a calculation is performed, if there is only ever one possible answer the calculation can be classified as a function.Įxample, not a function. ![]() ![]() Definition: A function is any relation (set of ordered pairs) whereby for each element in the domain, there is exactly one element in the range. ![]() |